Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nlrp3m5Btlr
Name:	NLR family, pyrin domain containing 3; mutation 5, Bruce Beutler
MGI ID:	MGI:5466146
Synonyms:	Park2
Gene:	Nlrp3  Location: Chr11:59432395-59457781 bp, + strand  Genetic Position: Chr11, 37.73 cM, cytoband B1.3
Alliance:	Nlrp3m5Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU-induced a C to T transition at base pair 59378630 (v37) on Chromosome 11 in the GenBank genomic region NC_000077. The mutation corresponds to residue 2749 in the cDNA (ENSMUST00000079476) in exon 9 of 11. The mutation causes an arginine to a premature stop codon change in the protein at residue 917 of the protein. (J:192651)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nlrp3 Mutation:	61 strains or lines available

Original:	J:192651 Beutler B, Direct Data Submission. MGI Direct Data Submission. 2013;
All:	1 reference(s)