Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tab2tm2.1Aki
Name:	TGF-beta activated kinase 1/MAP3K7 binding protein 2; targeted mutation 2.1, Shizuo Akira
MGI ID:	MGI:5464099
Synonyms:	TAB2flox
Gene:	Tab2  Location: Chr10:7781417-7831994 bp, - strand  Genetic Position: Chr10, 2.56 cM
Alliance:	Tab2tm2.1Aki page

Germline Transmission:	Earliest citation of germline transmission: J:81816
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Flanking loxP sites were introduced to the large exon and a floxed neo cassette was inserted into the upstream intron. Cre-mediated recombination removed the neo cassette and left the exon floxed. (J:81816)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tab2 Mutation:	31 strains or lines available

Original:	J:81816 Sanjo H, et al., TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling. Mol Cell Biol. 2003 Feb;23(4):1231-8
All:	7 reference(s)