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Uimc1tm1.1Amj
Targeted Allele Detail
Summary
Symbol: Uimc1tm1.1Amj
Name: ubiquitin interaction motif containing 1; targeted mutation 1.1, Anton M Jetten
MGI ID: MGI:5463913
Synonyms: RAP80fx
Gene: Uimc1  Location: Chr13:55175693-55248113 bp, - strand  Genetic Position: Chr13, 29.8 cM, cytoband B2
Alliance: Uimc1tm1.1Amj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:191827
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 4 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 6 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:191827)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Uimc1 Mutation:  34 strains or lines available
References
Original:  J:191827 Yin Z, et al., RAP80 is critical in maintaining genomic stability and suppressing tumor development. Cancer Res. 2012 Oct 1;72(19):5080-90
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory