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Tg(Acta2-cre/ERT2)1Ikal
Transgene Detail
Nomenclature
Symbol: Tg(Acta2-cre/ERT2)1Ikal
Name: transgene insertion 1, Ivo Kalajzic
MGI ID: MGI:5461154
Synonyms: alphaSMACreERT2
Transgene: Tg(Acta2-cre/ERT2)1Ikal  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsThe cre/ERT2 cDNA and BGH polyA cDNAs was inserted into a construct containing the vascular smooth muscle alpha-actin (Acta2) promoter. Functionality of the construct to modify floxed reporter constructs was tested by transient transfection of smooth muscle cell cultures. The purified vector was injected into fertilized C57BL/6 oocytes. (J:190191)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Acta2     Summary of all recombinase alleles driven by Acta2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:190191 Grcevic D, et al., In vivo fate mapping identifies mesenchymal progenitor cells. Stem Cells. 2012 Feb;30(2):187-96
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory