Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Acta2-cre/ERT2)1Ikal
Name:	transgene insertion 1, Ivo Kalajzic
MGI ID:	MGI:5461154
Synonyms:	alphaSMACreERT2
Transgene:	Tg(Acta2-cre/ERT2)1Ikal  Location: unknown
Alliance:	Tg(Acta2-cre/ERT2)1Ikal page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Acta2-cre/ERT2)1Ikal expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Acta2   Mutation details: The cre/ERT2 cDNA and BGH polyA cDNAs was inserted into a construct containing the vascular smooth muscle alpha-actin (Acta2) promoter. Functionality of the construct to modify floxed reporter constructs was tested by transient transfection of smooth muscle cell cultures. The purified vector was injected into fertilized C57BL/6 oocytes. (J:190191)

Activity:	Tissue activity of this recombinase allele
Driver:	Acta2 (species not specified) Summary of all recombinase alleles driven by Acta2. Comparative matrix view of recombinase activities

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:190191 Grcevic D, et al., In vivo fate mapping identifies mesenchymal progenitor cells. Stem Cells. 2012 Feb;30(2):187-96
All:	13 reference(s)