Foxp3tm10.1(Casp9,-Thy1)Ayr
Targeted Allele Detail
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| Symbol: |
Foxp3tm10.1(Casp9,-Thy1)Ayr |
| Name: |
forkhead box P3; targeted mutation 10.1, Alexander Y Rudensky |
| MGI ID: |
MGI:5451201 |
| Synonyms: |
Foxp3-IRES-iCasp9, Foxp3Thy1.1, Foxp3-Thy1.1 |
| Gene: |
Foxp3 Location: ChrX:7445915-7461482 bp, + strand Genetic Position: ChrX, 3.41 cM
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| Alliance: |
Foxp3tm10.1(Casp9,-Thy1)Ayr page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:191041
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: A construct containing an IRES, indubible Caspase9, T2A cleavage site, Thy1, polyadenylation signal sequence, and FRT-flanked neomycin resistance gene cassette was inserted into the 3' UTR. Flp-mediated recombination removed the neo cassette.
(J:191041)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Foxp3 Mutation: |
55 strains or lines available
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| Original: |
J:191041 Liston A, et al., Differentiation of regulatory Foxp3+ T cells in the thymic cortex. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11903-8 |
| All: |
25 reference(s) |
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Analysis Tools
