Foxo1<tm1.1Moli> Targeted Allele Detail MGI Mouse (MGI:5447984)

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Foxo1^tm1.1Moli
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Summary

Symbol:	Foxo1^tm1.1Moli
Name:	forkhead box O1; targeted mutation 1.1, Ming O Li
MGI ID:	MGI:5447984
Synonyms:	Foxo1^tag
Gene:	Foxo1 Location: Chr3:52175758-52257530 bp, + strand Genetic Position: Chr3, 23.19 cM
Alliance:	Foxo1^tm1.1Moli page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:189962
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutation:		Insertion
		Mutation details: An GFP, FLAG and biotin tag was added to exon 2. Cre-mediated recombination removed the floxed neo cassette inserted downstream of the modified exon 2. (J:189962)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Foxo1 Mutation:	31 strains or lines available

References

Original:	J:189962 Ouyang W, et al., Novel Foxo1-dependent transcriptional programs control T(reg) cell function. Nature. 2012 Nov 22;491(7425):554-9
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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