Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Il23rtm1.1Trin
Name:	interleukin 23 receptor; targeted mutation 1.1, Giorgio Trinchieri
MGI ID:	MGI:5446607
Synonyms:	Il23rF
Gene:	Il23r  Location: Chr6:67399916-67468839 bp, - strand  Genetic Position: Chr6, 30.85 cM
Alliance:	Il23rtm1.1Trin page

Germline Transmission:	Earliest citation of germline transmission: J:189226
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed loxP site was inserted upstream of exon 2. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 3. Flp- and cre-mediated recombination removed the neo cassettes and left exons 2 and 3 floxed. (J:189226)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il23r Mutation:	68 strains or lines available

Original:	J:189226 Grivennikov SI, et al., Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature. 2012 Nov 8;491(7423):254-8
All:	1 reference(s)