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Hsf1tm1.1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Hsf1tm1.1(KOMP)Vlcg
Name: heat shock factor 1; targeted mutation 1.1, Velocigene
MGI ID: MGI:5445761
Gene: Hsf1  Location: Chr15:76361562-76385355 bp, + strand  Genetic Position: Chr15, 35.95 cM
Mutation
origin
Mutant Cell Line:  15769A-B10
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 23063bp between positions 76308034-76331096 of Chromosome 15 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 54 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hsf1 Mutation:  16 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory