Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Insl5tm1Imad
Name:	insulin-like 5; targeted mutation 1, Ibrahim M Adham
MGI ID:	MGI:5445709
Gene:	Insl5  Location: Chr4:102875069-102884039 bp, - strand  Genetic Position: Chr4, 47.27 cM, cytoband C5-C7
Alliance:	Insl5tm1Imad page

Germline Transmission:	Earliest citation of germline transmission: J:189146
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo cassette replaced exon 2. Northern blot and RT-PCR analysis confirmed the absence of transcript expression in the rectum. (J:189146)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Insl5 Mutation:	14 strains or lines available

Original:	J:189146 Burnicka-Turek O, et al., INSL5-deficient mice display an alteration in glucose homeostasis and an impaired fertility. Endocrinology. 2012 Oct;153(10):4655-65
All:	1 reference(s)