Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gad1tm1.1(tTA2)Kftnk
Name:	glutamate decarboxylase 1; targeted mutation 1.1, Kenji Tanaka
MGI ID:	MGI:5439170
Synonyms:	GAD67-tTA
Gene:	Gad1  Location: Chr2:70391644-70432358 bp, + strand  Genetic Position: Chr2, 41.63 cM, cytoband D
Alliance:	Gad1tm1.1(tTA2)Kftnk page

Germline Transmission:	Earliest citation of germline transmission: J:186771
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Transactivator) Mutation:    Insertion   Mutation details: The tTA2 tetracycline transactivator containing modified VP16 activation domains was inserted into exon 3 along with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. (J:186771)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gad1 Mutation:	64 strains or lines available

Original:	J:186771 Tanaka KF, et al., Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep. 2012 Aug 30;2(2):397-406
All:	2 reference(s)