Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Htr5btm1.1(tTA)Kftnk
Name:	5-hydroxytryptamine (serotonin) receptor 5B; targeted mutation 1.1, Kenji Tanaka
MGI ID:	MGI:5439167
Synonyms:	Htr5btm1(tTA)Rhn, Htr5B-tTA
Gene:	Htr5b  Location: Chr1:121437571-121456194 bp, - strand  Genetic Position: Chr1, 52.98 cM, cytoband E4-G
Alliance:	Htr5btm1.1(tTA)Kftnk page

Germline Transmission:	Earliest citation of germline transmission: J:186771
Parent Cell Line:	CSL3 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Transactivator) Mutation:    Insertion   Mutation details: The mammalianized tetracycline transactivator (tTA), polyadenylation sequence and floxed neo cassette were inserted at the translation initation site. Cre-mediated recombination removed the neo cassette. (J:186771)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Htr5b Mutation:	20 strains or lines available

Original:	J:186771 Tanaka KF, et al., Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep. 2012 Aug 30;2(2):397-406
All:	7 reference(s)