Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	AlplALPLD1
Name:	alkaline phosphatase, liver/bone/kidney; alkaline phosphatase low level dominant 1
MGI ID:	MGI:5438641
Synonyms:	ALP-01
Gene:	Alpl  Location: Chr4:137469044-137523695 bp, - strand  Genetic Position: Chr4, 70.02 cM
Alliance:	AlplALPLD1 page

Strain of Origin:

C3HeB/FeJ

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis resulted in an A to G transition at nucleotide position 326 of exon5. This caused an aspartic acid to glycine change in codon 109. (J:187875) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Alpl Mutation:	351 strains or lines available

Original:	J:68708 Hrabe de Angelis MH, et al., Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet. 2000 Aug;25(4):444-7
All:	2 reference(s)