Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Cul4btm1Swl
Name:	cullin 4B; targeted mutation 1, Shu-Wha Lin
MGI ID:	MGI:5438236
Synonyms:	Cul4blox
Gene:	Cul4b  Location: ChrX:37622151-37665073 bp, - strand  Genetic Position: ChrX, 22.81 cM, cytoband A2
Alliance:	Cul4btm1Swl page

Germline Transmission:	Earliest citation of germline transmission: J:187403
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. (J:187403)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cul4b Mutation:	37 strains or lines available

Original:	J:187403 Chen CY, et al., Rescue of the genetically engineered Cul4b mutant mouse as a potential model for human X-linked mental retardation. Hum Mol Genet. 2012 Oct 1;21(19):4270-85
All:	3 reference(s)