About   Help   FAQ
Del(16App-Runx1)5Yah
Targeted Allele Detail
Summary
Symbol: Del(16App-Runx1)5Yah
Name: deletion, Chr 16, Yann Herault 5
MGI ID: MGI:5431211
Synonyms: Del5Yah, Ms5Yah
Gene: Del(16App-Runx1)5Yah  Location: Chr16:84749554-92622962 bp  Genetic Position: Chr16, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185269
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Intergenic deletion, Intragenic deletion
  Del(16App-Runx1)5Yah involves 149 genes/genome features (Gm27295, Gm22933, Gm23587 ...) View all
 
Mutation detailsTargeted meiotic recombination (TAMERE) removed the genomic sequence, including 46 genes, between loxP sites inserted into App and Runx1. (J:185269)
Generation of the Del(16App-Runx1)5Yah mouse model
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(16App-Runx1)5Yah Mutation:  0 strains or lines available
References
Original:  J:185269 Raveau M, et al., The app-runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a down syndrome mouse model. PLoS Genet. 2012 May;8(5):e1002724
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory