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Pik3ap1m1Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Pik3ap1m1Btlr
Name: phosphoinositide-3-kinase adaptor protein 1; mutation 1, Bruce Beutler
MGI ID: MGI:5429067
Synonyms: sothe
Gene: Pik3ap1  Location: Chr19:41272541-41385102 bp, - strand  Genetic Position: Chr19, 34.61 cM, cytoband D1
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU-mutagenesis induced an A to T transversion that results in the amino acid substitution of a STOP codon for lysine at position 496 (K496X). (J:185495)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pik3ap1 Mutation:  33 strains or lines available
References
Original:  J:185495 Arnold CN, et al., A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12286-93
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory