Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pik3ap1m1Btlr
Name:	phosphoinositide-3-kinase adaptor protein 1; mutation 1, Bruce Beutler
MGI ID:	MGI:5429067
Synonyms:	sothe
Gene:	Pik3ap1  Location: Chr19:41260980-41373541 bp, - strand  Genetic Position: Chr19, 34.61 cM, cytoband D1
Alliance:	Pik3ap1m1Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU-mutagenesis induced an A to T transversion that results in the amino acid substitution of a STOP codon for lysine at position 496 (K496X). (J:185495)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pik3ap1 Mutation:	50 strains or lines available

Original:	J:185495 Arnold CN, et al., A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12286-93
All:	1 reference(s)