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Nr1d1tm1.1Rev
Targeted Allele Detail
Nomenclature
Symbol: Nr1d1tm1.1Rev
Name: nuclear receptor subfamily 1, group D, member 1; targeted mutation 1.1, Ronald M Evans
MGI ID: MGI:5426698
Synonyms: Rev-erb-alox
Gene: Nr1d1  Location: Chr11:98658758-98666159 bp, - strand  Genetic Position: Chr11, 62.66 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:183855
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 3. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 3 and 4 floxed. (J:183855)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr1d1 Mutation:  25 strains or lines available
References
Original:  J:183855 Cho H, et al., Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta. Nature. 2012 May 3;485(7396):123-7
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/14/2021
MGI 6.17
The Jackson Laboratory