Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pald1tm1Vlcg
Name:	phosphatase domain containing, paladin 1; targeted mutation 1, Velocigene
MGI ID:	MGI:5317962
Synonyms:	PaladinLacZ, Pald1-
Gene:	Pald1  Location: Chr10:61155435-61219309 bp, - strand  Genetic Position: Chr10, 32.19 cM, cytoband B4
Alliance:	Pald1tm1Vlcg page

Germline Transmission:	Earliest citation of germline transmission: J:181634
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A lacZ and floxed neo cassette replaced exons 1 through 18. Western blot analysis confirmed the absence of protein expression in the lungs. (J:181634)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	119 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pald1 Mutation:	40 strains or lines available

Original:	J:181634 Wallgard E, et al., Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development. Dev Dyn. 2012 Apr;241(4):770-86
All:	3 reference(s)