Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sema3dtm2.1(GFP/cre)Joe
Name:	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; targeted mutation 2.1, Jonthan Epstein
MGI ID:	MGI:5317896
Synonyms:	Sema3DGFPcre, Sema3dtm1.1(GFP/cre)Cjt
Gene:	Sema3d  Location: Chr5:12433352-12638915 bp, + strand  Genetic Position: Chr5, 3.97 cM, cytoband A2
Alliance:	Sema3dtm2.1(GFP/cre)Joe page

Germline Transmission:	Earliest citation of germline transmission: J:183083
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Recombinase) Mutations:    Insertion, Intragenic deletion   Sema3dtm2.1(GFP/cre)Joe expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Sema3d (MGI:1860118)   Mutation details: An eGFP/cre fusion gene and an Frt-flanked neo cassette was inserted into the Sema3d locus at the ATG codon, replacing the remaining exon 2 sequence by homologous recombination in TL-1 ES cells. The neo was deleted by crossing germline mutants to Flp-expressing mice. (J:183083)

Activity:	Tissue activity of this recombinase allele
Driver:	Sema3d (mouse) Summary of all recombinase alleles driven by Sema3d. Comparative matrix view of recombinase activities Alliance mouse Sema3d gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

22 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema3d Mutation:	53 strains or lines available

Original:	J:183083 Katz TC, et al., Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Dev Cell. 2012 Mar 13;22(3):639-50
All:	7 reference(s)