Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tgfb3tm1.1Moaz
Name:	transforming growth factor, beta 3; targeted mutation 1.1, Mohamad Azhar
MGI ID:	MGI:5313416
Gene:	Tgfb3  Location: Chr12:86103519-86125815 bp, - strand  Genetic Position: Chr12, 40.09 cM
Alliance:	Tgfb3tm1.1Moaz page

Germline Transmission:	Earliest citation of germline transmission: J:181226
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site and an FRT flanked MC1-neomycin selection cassette were inserted in intron 5 and a second loxP site was placed in intron 6. Exon 6 and the selection cassette were subsequently removed by cre excision. (J:181226)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgfb3 Mutation:	34 strains or lines available

Original:	J:181226 Doetschman T, et al., Generation of mice with a conditional allele for the transforming growth factor beta3 gene. Genesis. 2012 Jan;50(1):59-66
All:	1 reference(s)