Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Bst2tm1Bsz
Name:	bone marrow stromal cell antigen 2; targeted mutation 1, Paul Bieniasz
MGI ID:	MGI:5308813
Gene:	Bst2  Location: Chr8:71986899-71990100 bp, - strand  Genetic Position: Chr8, 34.43 cM
Alliance:	Bst2tm1Bsz page

Germline Transmission:	Earliest citation of germline transmission: J:180252
Parent Cell Line:	CY2.4 (ES Cell)
Strain of Origin:	B6(Cg)-Tyrc-2J

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted into exon 1. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the neo cassette. (J:180252)

Generation of the Bst2tm1Bsz and Bst2tm1.1Bsz alleles

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bst2 Mutation:	12 strains or lines available

Original:	J:180252 Liberatore RA, et al., Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18097-101
All:	1 reference(s)