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Pax3tm1Sjc
Targeted Allele Detail
Summary
Symbol: Pax3tm1Sjc
Name: paired box 3; targeted mutation 1, Simon J Conway
MGI ID: MGI:2385684
Synonyms: paxneo
Gene: Pax3  Location: Chr1:78077904-78173771 bp, - strand  Genetic Position: Chr1, 39.79 cM
Alliance: Pax3tm1Sjc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75127
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe exon encoding two thirds of the homeodomain was flanked by a single upstream loxP site and and a downstream floxed neo cassette. (J:75127)
Expression
In Mice Carrying this Mutation: 36 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax3 Mutation:  50 strains or lines available
References
Original:  J:75127 Koushik SV, et al., Generation of a conditional loxP allele of the Pax3 transcription factor that enables selective deletion of the homeodomain. Genesis. 2002 Feb;32(2):114-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory