About   Help   FAQ
Tinf2tm1.1Tdl
Targeted Allele Detail
Summary
Symbol: Tinf2tm1.1Tdl
Name: Terf1 (TRF1)-interacting nuclear factor 2; targeted mutation 1.1, Titia de Lange
MGI ID: MGI:5306667
Synonyms: TIN2F
Gene: Tinf2  Location: Chr14:55912146-55919277 bp, - strand  Genetic Position: Chr14, 28.19 cM
Alliance: Tinf2tm1.1Tdl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:178606
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 3. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neo cassette and left exons 3 through 7 floxed. (J:178606)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tinf2 Mutation:  14 strains or lines available
References
Original:  J:178606 Takai KK, et al., Telomere Protection by TPP1/POT1 Requires Tethering to TIN2. Mol Cell. 2011 Nov 18;44(4):647-59
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory