Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hes1tm1.1Sat
Name:	hes family bHLH transcription factor 1; targeted mutation 1.1, Spyros Artavanis-Tsakonas
MGI ID:	MGI:5304919
Synonyms:	Hes1-EmGFPSAT, Hes1-GFP
Gene:	Hes1  Location: Chr16:29883259-29886614 bp, + strand  Genetic Position: Chr16, 21.09 cM
Alliance:	Hes1tm1.1Sat page

Germline Transmission:	Earliest citation of germline transmission: J:179632
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to insert the open reading frame of emerald GFP (EmGFP), a polyadenylation sequence and an Frt-flanked neo selection cassette, resulting in replacement of the exon 1 coding region. Chimeric males were bred to Flpe-expressing females to excise the selection cassette. (J:179632)

Generation of the Hes1tm1.1Sat allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hes1 Mutation:	21 strains or lines available

Original:	J:179632 Fre S, et al., Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice. PLoS One. 2011;6(10):e25785
All:	10 reference(s)