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Wnt3atm1e(EUCOMM)Wtsi
Targeted Allele Detail
Summary
Symbol: Wnt3atm1e(EUCOMM)Wtsi
Name: wingless-type MMTV integration site family, member 3A; targeted mutation 1e, Wellcome Trust Sanger Institute
MGI ID: MGI:5301395
Gene: Wnt3a  Location: Chr11:59138859-59181578 bp, - strand  Genetic Position: Chr11, 37.17 cM
IMPC: Wnt3a gene page
Mutation
origin
Mutant Cell Lines:  EPD0040_3_D11, EPD0040_3_E12, EPD0040_3_G10
Germline Transmission:  Unknown
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt2
 
Mutation detailsThe L1L2_gt2 cassette was inserted at position 59166836 of Chromosome 11 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:155845, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt3a Mutation:  25 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory