Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1Vpa
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Vassilis Pachnis
MGI ID:	MGI:5301115
Synonyms:	R26RFP635
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1Vpa page

Germline Transmission:	Earliest citation of germline transmission: J:178239
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: A targeting vector contained the coding sequences of the red fluorescent protein FP635 downstream of a loxP-flanked neomycin resistance cassette containing three transcriptional stop signals. The construct was electroporated into R1 ES cells. Correctly targeted ES cells were used to establish the R26RFP635 reporter strain. (J:178239)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	944 strains or lines available

Original:	J:178239 Laranjeira C, et al., Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury. J Clin Invest. 2011 Sep 1;121(9):3412-24
All:	5 reference(s)