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Transgene Detail
Symbol: Tg(tetO-Stat5a*S710F,-luc)11676Kuw
Name: transgene insertion 11676, Kay-Uwe Wagner
MGI ID: MGI:5300600
Synonyms: TetO-Stat5(S710F)Flag-IRES-luciferase
Transgene: Tg(tetO-Stat5a*S710F,-luc)11676Kuw  Location: unknown  
Strain of Origin:  Not Specified
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Reporter)
Mutation:    Insertion
Mutation detailsThe tetracycline operator drives inducible expression of the FLAG-tagged mouse cDNA with a point mutation that results in an amino acid substitution of phenylalanine for serine at position 710 (S710F) and an IRES-luciferase reporter. Lines 11651 and 11676 were generated. (J:162571)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:162571 Creamer BA, et al., Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1. Mol Cell Biol. 2010 Jun;30(12):2957-70
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.04
The Jackson Laboratory