Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Pdgfrb-cre)35Vli
Name:	transgene insertion 35, Volkhard Lindner
MGI ID:	MGI:5291826
Synonyms:	PDGFRB-Cre(VL), Pdgfrbeta-Cre, Tg(Pdgfrb-cre)35Vli, Tg(Pdgfrb-Cre)45Vli
Transgene:	Tg(Pdgfrb-cre)35Vli  Location: unknown
Alliance:	Tg(Pdgfrb-cre)35Vli page

Strain of Origin:

FVB/N x B6;129S4-Gt(ROSA)26Sortm1Sor/J

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Pdgfrb-cre)35Vli expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Pdgfrb   Mutation details: The transgenic construct contained a 4.8 kb fragment of Pdgfrb including the promoter and the first exon fused to a nuclear-targeted cre recombinase sequence. The construct was injected into fertilized oocytes. Founders were crossed to Gt(ROSA)26Sortm1Sor reporter mice to analyze cre activity in embryonic and adult tissues. Line 35 was used for further experiments. (J:175492)

Activity:	Tissue activity of this recombinase allele
Driver:	Pdgfrb (species not specified) Summary of all recombinase alleles driven by Pdgfrb.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:175492 Cuttler AS, et al., Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries. Genesis. 2011 Aug;49(8):673-80
All:	22 reference(s)