Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hbb-bh2tm1(KOMP)Mbp
Name:	hemoglobin beta, bh2; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID:	MGI:5287764
Gene:	Hbb-bh2  Location: Chr7:103488331-103489727 bp, - strand  Genetic Position: Chr7, 54.85 cM
IMPC:	Hbb-bh2 gene page

Mutant Cell Lines:	DEPD00574_5_B04, DEPD00574_5_C03, DEPD00574_5_D02, DEPD00574_5_E01, DEPD00574_5_F01, DEPD00574_5_F04, DEPD00574_5_G02, DEPD00574_5_H01, DEPD00574_5_H02
Germline Transmission:	Unknown
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1344 starting at position 103488191 and ending at position 103489535 of Chromosome 7 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Hbb-bh2 Mutation:	16 strains or lines available

Original:	J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:	1 reference(s)