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Vegfatm2Nagy
Targeted Allele Detail
Summary
Symbol: Vegfatm2Nagy
Name: vascular endothelial growth factor A; targeted mutation 2, Andras Nagy
MGI ID: MGI:2383984
Synonyms: Vegflo+Neo
Gene: Vegfa  Location: Chr17:46327919-46343295 bp, - strand  Genetic Position: Chr17, 22.79 cM
Alliance: Vegfatm2Nagy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75937
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsA floxed PGK-neo cassette and an IRES-lacZ cassette were inserted adjacent to a stop codon in exon 8 via homologous recombination. (J:75937)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vegfa Mutation:  37 strains or lines available
References
Original:  J:75937 Damert A, et al., Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation. Development. 2002 Apr;129(8):1881-92
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory