Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Oprl1tm1Hta
Name:	opioid receptor-like 1; targeted mutation 1, Hiroshi Takeshima
MGI ID:	MGI:2181784
Synonyms:	morcm1, NOP-, NOP-R-, NOR-, ORL1
Gene:	Oprl1  Location: Chr2:181356809-181362778 bp, + strand  Genetic Position: Chr2, 103.74 cM, cytoband H2-4
Alliance:	Oprl1tm1Hta page

Germline Transmission:	Earliest citation of germline transmission: J:39955
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The gene was disrupted by replacement of an exon with a lacZ-neo cassette via homologous recombination. Northern blot analysis of brain from homozygous mutant animals confirmed the absence of gene expression. (J:39955)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprl1 Mutation:	26 strains or lines available

Original:	J:39955 Nishi M, et al., Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor. EMBO J. 1997 Apr 15;16(8):1858-64
All:	34 reference(s)