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Gt(ROSA)26Sortm1(CAG-EGFP)Blh
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(CAG-EGFP)Blh
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Brigid L Hogan
MGI ID: MGI:3850169
Synonyms: GFPf, Rosa26R-CAG-fGFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(CAG-EGFP)Blh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149822
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsA construct containing the chicken beta-actin promoter (CAG) with a loxP-STOP-loxP cassette preceding a farnesylated enhanced GFP sequence (eGFP-f) was inserted into intron 1 of the Gt(ROSA)26Sor locus via homologous recombination. Cre-mediated recombination of this allele results in the expression of the EGFP reporter driven by the CAG promoter. (J:149822)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Gt(ROSA)26Sortm1(CAG-EGFP)Blh
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:149822 Rawlins EL, et al., The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell. 2009 Jun 5;4(6):525-34
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory