Efnb1tm2.1Sor
Targeted Allele Detail
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Symbol: |
Efnb1tm2.1Sor |
Name: |
ephrin B1; targeted mutation 2.1, Philippe Soriano |
MGI ID: |
MGI:3850100 |
Synonyms: |
Ephrin-B1lox6F |
Gene: |
Efnb1 Location: ChrX:98179736-98192597 bp, + strand Genetic Position: ChrX, 43.22 cM, cytoband D
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Alliance: |
Efnb1tm2.1Sor page
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Germline Transmission: |
Earliest citation of germline transmission:
J:150043
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Parent Cell Line: |
AK7.1 (ES Cell)
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Strain of Origin: |
129S4/SvJaeSor
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutations: |
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Insertion, Nucleotide substitutions
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Mutation details: Germ line, flp mediated recombination removed the neo cassette leaving exon 5 floxed and the modified exon 5 not expressed. Cre mediated recombination to remove the wild-type exon 5 is needed to allow for expression of the modified exon 5.
(J:150043)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Efnb1 Mutation: |
15 strains or lines available
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Original: |
J:150043 Bush JO, et al., Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99 |
All: |
1 reference(s) |
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