Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Or10a4tm2(Or7a40)Mom
Name:	olfactory receptor family 10 subfamily A member 4; targeted mutation 2, Peter Mombaerts
MGI ID:	MGI:2179504
Synonyms:	M12->P2-IRES-tau-lacZ, Or10a4tm2(Olfr19)Mom
Gene:	Or10a4  Location: Chr7:106696674-106697621 bp, + strand  Genetic Position: Chr7, 56.1 cM, cytoband F2
Alliance:	Or10a4tm2(Or7a40)Mom page

Germline Transmission:	Earliest citation of germline transmission: J:36595
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted Mutation:    Insertion   Mutation details: The coding region for Olfr19, modified by introduction of the hemagglutinin epitope tag between the second and third exon, was linked to the 5' end of an IRES-tau-lacZ-loxP-tk-neo-loxP expression cassette. Insertion of this construct replaced the entire translated region of the endogenous gene, and placed expression of the inserted sequences under control of the endogenous regulatory sequences. Transient expression of Cre recombinase in C57BL/6 blastocysts excised the thymidine kinase and neomycin sequences. This allele expresses a bicistronic mRNA encoding Olfr19 and a bovine tau-beta-galactosidase fusion protein. (J:36595)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Or10a4 Mutation:	22 strains or lines available

Original:	J:36595 Mombaerts P, et al., Visualizing an olfactory sensory map. Cell. 1996 Nov 15;87(4):675-86
All:	1 reference(s)