Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Hspa2-cre)1Eddy
Name:	transgene insertion 1, Edward M Eddy
MGI ID:	MGI:3843498
Synonyms:	Hspa2cre, Hspa2-cre, Hspa2-cre line 54
Transgene:	Tg(Hspa2-cre)1Eddy  Location: unknown
Alliance:	Tg(Hspa2-cre)1Eddy page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Hspa2-cre)1Eddy expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Hspa2 (MGI:96243)   Mutation details: The Hspa2-Cre transgene was designed with (from 5' to 3') a 53 bp mouse Acrv1 (acrosomal vesicle protein 1 [SP-10]) insulator element, a promoter element from the mouse Hspa2 locus (heat shock protein 2 [Hsp70-2]); containing the ATG start site and 892 bp of immediately upstream sequence), a 275 bp fragment of the cre gene, the bovine growth hormone 3' UTR and polyA sequence, and another 53 bp mouse Acrv1 insulator element. This transgene was injected into C57BL/6 pronuclear stage embryos. Expression of Cre recombinase is directed to the developing male germ cells. (J:148085, J:156314)

Activity:	Tissue activity of this recombinase allele
Driver:	Hspa2 (mouse) Summary of all recombinase alleles driven by Hspa2. Comparative matrix view of recombinase activities Alliance mouse Hspa2 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:156314 Inselman AL, et al., Heat shock protein 2 promoter drives cre expression in spermatocytes of transgenic mice. Genesis. 2010 Feb;48(2):114-20
All:	19 reference(s)