Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm2(CAG-luc)Tyj
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Tyler Jacks
MGI ID:	MGI:5140917
Synonyms:	Gt(ROSA)26Sortm2(ACTB-luc)Tyj
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm2(CAG-luc)Tyj page

Germline Transmission:	Earliest citation of germline transmission: J:174756
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: A cassette containing a CAG promoter and a floxed STOP followed by a luciferase gene was inserted into the locus. Cre-mediated recombination is necessary to allow for expression of luciferase under the control of the CAG promoter. (J:174756)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	944 strains or lines available

Original:	J:174756 Dooley AL, et al., Nuclear factor I/B is an oncogene in small cell lung cancer. Genes Dev. 2011 Jul 15;25(14):1470-5
All:	7 reference(s)