Pdgfrbtm13.1(Pdgfrb)Sor
Targeted Allele Detail
|
Symbol: |
Pdgfrbtm13.1(Pdgfrb)Sor |
Name: |
platelet derived growth factor receptor, beta polypeptide; targeted mutation 13.1, Philippe Soriano |
MGI ID: |
MGI:5140878 |
Synonyms: |
PDGFRbetaJ |
Gene: |
Pdgfrb Location: Chr18:61178222-61218133 bp, + strand Genetic Position: Chr18, 34.41 cM
|
Alliance: |
Pdgfrbtm13.1(Pdgfrb)Sor page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:173602
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Inserted expressed sequence) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: Exons 2 and 3 were replaced with a splice acceptor, floxed neo/stop cassette, and mouse cDNA with nucleotide substitution(s) that results in the amino acid substitution of alanine for valine at position 536 (V536A). Cre-mediated recombination removed the neo/stop cassette.
(J:173602)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Pdgfrb Mutation: |
84 strains or lines available
|
|
Original: |
J:173602 Olson LE, et al., PDGFRbeta Signaling Regulates Mural Cell Plasticity and Inhibits Fat Development. Dev Cell. 2011 Jun 14;20(6):815-26 |
All: |
2 reference(s) |
|