Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1.3(CAG-EGFP)Glh
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1.3, David J Goldhamer
MGI ID:	MGI:3840214
Synonyms:	R26G
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1.3(CAG-EGFP)Glh page

Germline Transmission:	Earliest citation of germline transmission: J:147304
Parent Cell Line:	D1 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6J)F1

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: A vector containing a CAG promoter driving expression of a floxed neo/STOP cassette, frt flanked lacZ gene with 3 polyadenylation sequences (secondary STOP cassette), and an EGFP gene was inserted into the locus. Germ line, cre and flp mediated recombination removes the neo/STOP and lacZ/STOP cassettes allowing for ubiquitous expression of EGFP. (J:147304)

Generation of Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh, Gt(ROSA)26Sortm1.1(CAG-lacZ,-EGFP)Glh, Gt(ROSA)26Sortm1.2(CAG-EGFP)Glh, and Gt(ROSA)26Sortm1.3(CAG-EGFP)Glh alleles

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	944 strains or lines available

Original:	J:147304 Yamamoto M, et al., A multifunctional reporter mouse line for Cre- and FLP-dependent lineage analysis. Genesis. 2009 Feb;47(2):107-14
All:	3 reference(s)