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Tead2tm1e(EUCOMM)Hmgu
Targeted Allele Detail
Nomenclature
Symbol: Tead2tm1e(EUCOMM)Hmgu
Name: TEA domain family member 2; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:5052473
Gene: Tead2  Location: Chr7:45215753-45233636 bp, + strand  Genetic Position: Chr7, 29.19 cM, cytoband B5
Mutation
origin
Mutant Cell Lines:  HEPD0745_4_B09, HEPD0745_4_C09, HEPD0745_4_C10, HEPD0745_4_C11, HEPD0745_4_E10, HEPD0745_4_F10, HEPD0745_4_H11, HEPD0745_4_H12
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 45217537 of Chromosome 7 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Tead2 Mutation:  20 strains or lines available
References
Original:  J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory