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Tg(Cyp39a1-cre)1Aibs
Transgene Detail
Nomenclature
Symbol: Tg(Cyp39a1-cre)1Aibs
Name: transgene insertion 1, Ed Lein
MGI ID: MGI:3838493
Synonyms: Cyp39a1-Tg1-Cre
Transgene: Tg(Cyp39a1-cre)1Aibs  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F1 x C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe 206 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-370M9, containing the entire Cyp39a1 locus (and other genes), was modified by targeting a Cre recombinase coding sequence (the CreERT2 sequence modified back to encode the normal Cre recombinase gene), SV40 polyA signal, and frt-flanked neomycin cassette to the ATG start site of the Cyp39a1 locus. The targeted BAC sequences were further modified using FLP recombination to remove the selection cassette and linearized to remove its original vector backbone. Cre expression is directed to cortex, hippocampus and cerebellum by the Cyp39a1 promoter/enhancer regions within the BAC transgene. (J:146821)
Recombinase
activity
Activity:
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Driver: Cyp39a1     Summary of all recombinase alleles driven by Cyp39a1. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:146821 Allen Institute for Brain Science, Cre transgenes and knockin alleles created at the Allen Insitute for Brain Science (AIBS). MGI Direct Data Submission. 2009-17;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory