Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm4(Dll1)Sat
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Spyros Artavanis-Tsakonas
MGI ID:	MGI:5007807
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm4(Dll1)Sat page

Germline Transmission:	Earliest citation of germline transmission: J:171887
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Conditional ready, Inserted expressed sequence) Mutation:    Insertion   Gt(ROSA)26Sortm4(Dll1)Sat expresses 1 gene Knock-in expresses: Organism Expressed Gene Note mouse Dll1 (MGI:104659)   Mutation details: A targeting vector containing a splice acceptor site, a floxed PGK neomycin cassette, and a mouse Dll1 cDNA was inserted via homologous recombination. (J:171887)

Schematic of the Gt(ROSA)26Sortm4(Dll1)Sat construct

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:171887 Arboleda-Velasquez JF, et al., PNAS Plus: Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proc Natl Acad Sci U S A. 2011 May 24;108(21):E128-35
All:	2 reference(s)