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Gt(ROSA)26Sortm4.1(CAG-lacZ)Dym
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm4.1(CAG-lacZ)Dym
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4.1, Susan M Dymecki
MGI ID: MGI:5006934
Synonyms: RC::Fa
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm4.1(CAG-lacZ)Dym page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136096
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsGerm-line cre deletion of the loxP-flanked EGFP cassette generated this Flp only-responsive reporter allele. In presence of Flp (or Flpe), the Frt-flanked PGK-Neo stop cassette is excised allowing expression of lacZ in Flp-expression progenitor cells.
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:136096 Jensen P, et al., Redefining the serotonergic system by genetic lineage. Nat Neurosci. 2008 Apr;11(4):417-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory