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Gt(ROSA)26Sortm1(GAP43/EGFP)Gld
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(GAP43/EGFP)Gld
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Martyn Goulding
MGI ID: MGI:3835484
Synonyms: R26GAP43-EGFP, ROSA-GAP43-eGFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(GAP43/EGFP)Gld page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87771
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsA floxed STOP cassette preceding a GAP43/EGFP fusion cDNA was inserted into the locus. Cre mediated removal of the STOP cassette is necessary for expression of the fusion gene in V1-derived neurons. (J:87771)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:87771 Sapir T, et al., Pax6 and engrailed 1 regulate two distinct aspects of renshaw cell development. J Neurosci. 2004 Feb 4;24(5):1255-64
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory