Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Egfrtm1.1Dwt
Name:	epidermal growth factor receptor; targeted mutation 1.1, David W Threadgill
MGI ID:	MGI:3834077
Synonyms:	Egfrdelta
Gene:	Egfr  Location: Chr11:16702203-16868158 bp, + strand  Genetic Position: Chr11, 9.41 cM, cytoband A1-A4
Alliance:	Egfrtm1.1Dwt page

Germline Transmission:	Earliest citation of germline transmission: J:145069
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination was used to remove exon 3. The absence of protein expression was confirmed by western blot analysis on dorsal root ganglion extracts. (J:145151)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Egfr Mutation:	85 strains or lines available

Original:	J:145069 Maklad A, et al., The EGFR is required for proper innervation to the skin. J Invest Dermatol. 2009 Mar;129(3):690-8
All:	5 reference(s)