Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol: Gng7tm2(cre/PGR)Mmsh Name: guanine nucleotide binding protein (G protein), gamma 7; targeted mutation 2, Masayoshi Mishina MGI ID: MGI:3833956 Synonyms: Gng7mCrePR Gene: Gng7  Location: Chr10:80784463-80850742 bp, - strand  Genetic Position: Chr10, 39.72 cM Alliance: Gng7tm2(cre/PGR)Mmsh page

Ablation of medium-spiny projection neurons in the striatum of Gng7tm2(cre/PGR)Mmsh/Gng7+ Eno2tm1(DTA)Hsak/Eno2+ mice Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:145152
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    mifepristone Mutation:    Insertion   Gng7tm2(cre/PGR)Mmsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gng7 (MGI:95787)   Mutation details: An inducible cre cassette consisting of mammalian optimized cre fused to the human progesterone receptor followed by a neo selection cassette in the inverse orientation were inserted into the translation initiation site via homologous recombination. Following RU-496 treatment no Cre activity was detected in brain slices. (J:145152)

Generation of the Gng7tm1(cre)Mmsh and Gng7tm2(cre/PGR)Mmsh alleles

Activity:	Tissue activity of this recombinase allele
Driver:	Gng7 (mouse) Summary of all recombinase alleles driven by Gng7. Alliance mouse Gng7 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gng7 Mutation:	75 strains or lines available

Original:	J:145152 Kishioka A, et al., A novel form of memory for auditory fear conditioning at a low-intensity unconditioned stimulus. PLoS One. 2009;4(1):e4157
All:	3 reference(s)