Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc6a3tm3(tetO)Xz
Name:	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; targeted mutation 3, Xiaoxi Zhuang
MGI ID:	MGI:3832294
Synonyms:	tetO-DAT
Gene:	Slc6a3  Location: Chr13:73684866-73726791 bp, + strand  Genetic Position: Chr13, 40.1 cM
Alliance:	Slc6a3tm3(tetO)Xz page

Germline Transmission:	Earliest citation of germline transmission: J:144671
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Hypomorph) Mutation:    Insertion   Mutation details: The tetracycline promoter was inserted into the 5' untranslated region. Expression is reduced to 5% of wild-type. This is a hypomorphic allele. (J:144671)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc6a3 Mutation:	66 strains or lines available

Original:	J:144671 Cagniard B, et al., Dopamine scales performance in the absence of new learning. Neuron. 2006 Sep 7;51(5):541-7
All:	1 reference(s)