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Gt(ROSA)26Sortm1(Foxo1/GFP)Jke
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(Foxo1/GFP)Jke
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Joel K Elmquist
MGI ID: MGI:3830706
Synonyms: Rosa26-FoxoGFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(Foxo1/GFP)Jke page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143046
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsA floxed neo-STOP cassette followed by a Foxo1/GFP fusion was inserted into the locus. Expression of the reporter construct can only be achieved by cre-mediated removal of the neo-STOP cassette. (J:143046)
Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  944 strains or lines available
References
Original:  J:143046 Fukuda M, et al., Monitoring FoxO1 localization in chemically identified neurons. J Neurosci. 2008 Dec 10;28(50):13640-8
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory