Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm2.1(Cd74/MOG)Awai
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Ari Waisman
MGI ID:	MGI:3814860
Synonyms:	IiMOG
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm2.1(Cd74/MOG)Awai page

Germline Transmission:	Earliest citation of germline transmission: J:140751
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted Mutation:    Insertion   Mutation details: Cre-mediated recombination removed the STOP cassette and allow for expression of the Cd74-MOG fusion. (J:140751)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:140751 Frommer F, et al., Tolerance without clonal expansion: self-antigen-expressing B cells program self-reactive T cells for future deletion. J Immunol. 2008 Oct 15;181(8):5748-59
All:	3 reference(s)