Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Foxp3tm9(EGFP/cre/ERT2)Ayr
Name:	forkhead box P3; targeted mutation 9, Alexander Y Rudensky
MGI ID:	MGI:4950935
Synonyms:	Foxp3eGFP-Cre-ERT2, Foxp3-GFP-Cre
Gene:	Foxp3  Location: ChrX:7445915-7461482 bp, + strand  Genetic Position: ChrX, 3.41 cM
Alliance:	Foxp3tm9(EGFP/cre/ERT2)Ayr page

Germline Transmission:	Earliest citation of germline transmission: J:171734
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Foxp3tm9(EGFP/cre/ERT2)Ayr expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Foxp3 (MGI:1891436)   Mutation details: An IRES element followed by an EGFP-cre-ERT2 coding sequence was knocked into the 3' UTR of the Foxp3 locus. (J:171734)

Activity:	Tissue activity of this recombinase allele
Driver:	Foxp3 (mouse) Summary of all recombinase alleles driven by Foxp3. Alliance mouse Foxp3 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxp3 Mutation:	55 strains or lines available

Original:	J:171734 Rubtsov YP, et al., Stability of the regulatory T cell lineage in vivo. Science. 2010 Sep 24;329(5999):1667-71
All:	68 reference(s)