Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hdac2tm1.1Eem
Name:	histone deacetylase 2; targeted mutation 1.1, Edward E Morrisey
MGI ID:	MGI:4950697
Synonyms:	HDAC2loxP
Gene:	Hdac2  Location: Chr10:36850540-36877885 bp, + strand  Genetic Position: Chr10, 19.44 cM, cytoband B1
Alliance:	Hdac2tm1.1Eem page

Germline Transmission:	Earliest citation of germline transmission: J:171358
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette. (J:171358)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hdac2 Mutation:	38 strains or lines available

Original:	J:171358 Anokye-Danso F, et al., Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency. Cell Stem Cell. 2011 Apr 8;8(4):376-88
All:	3 reference(s)