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Hoxb4tm1.1Mev
Targeted Allele Detail
Summary
Symbol: Hoxb4tm1.1Mev
Name: homeobox B4; targeted mutation 1.1, Alexander Medvinsky
MGI ID: MGI:4949668
Synonyms: Hoxb4YFP
Gene: Hoxb4  Location: Chr11:96209093-96212464 bp, + strand  Genetic Position: Chr11, 59.83 cM
Alliance: Hoxb4tm1.1Mev page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170503
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsYFP and an FRT-flanked EM7-blasticidin selection marker cassette were inserted upstream of exon 1. Flp-mediated recombination removed the selection cassette. (J:170503)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb4 Mutation:  18 strains or lines available
Notes
ES cell line = CGR14 (129/Sv)
References
Original:  J:170503 Hills D, et al., Hoxb4-YFP reporter mouse model: a novel tool for tracking HSC development and studying the role of Hoxb4 in hematopoiesis. Blood. 2011 Mar 31;117(13):3521-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory